Comparison between drugs on hemodynamic changes during tracheal intubation

Comparison of dexmedetomidine and remifentanil for attenuation of hemodynamic responses to laryngoscopy and orotracheal intubation

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016092722254N1

Enrollment

124

Registered

2016-11-26

Start date

2016-06-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation. other medical peocedures

Interventions

Intervention 1: We injected 1 micro gram per kilogram Dexmedetomidin in first group. Intervention 2: We injected ?3 cc of Saline in second group. Intervention 3: We injected 1 micro gram per kilogram

Treatment - Drugs

We injected 1 micro gram per kilogram Dexmedetomidin in first group

We injected ?3 cc of Saline in second group.

We injected 1 micro gram per kilogram Remifentanil in third group.

We inject 0/5 micro gram per kilogram Dexmedetomidin and Remifentanil in fourth group.

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA I and II; without chronic disease; lack of drug abuse; age 18-75; both of gender Exclusion criteria: Unwillingness to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure. Timepoint: before and after inubation. Method of measurement: Blood pressure manometer.;Oxygenation. Timepoint: before and after inubation. Method of measurement: Pulse Oxymetery.;Heart rate. Timepoint: before and after inubation. Method of measurement: number in minute.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamaldin Modir

Arak University of Medical Sciences

dr.hemodir@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026