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Comparison of the Clinical pregnancy outcomes of ovarian stimulation with hMG + rFSH or rFSH + rLH methods in infertile patients.

Comparison of the clinical outcome of ovarian stimulation with hMG + rFSH versus rFSH + rLH in infertile patients undergoing IVF / ICSI .

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016092720351N3
Enrollment
140
Registered
2016-10-31
Start date
2014-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility associated with anovulation. Female infertility, unspecified

Interventions

Intervention 1: TheFirst Interven group (n=70) , received oral contraceptive, GnRH, rFSH and rLH ,150-300 unit subcutaneously. Intervention 2: The second Intervention group (n=70) received oral co
Treatment - Drugs
TheFirst Interven group (n=70) , received oral contraceptive, GnRH, rFSH and rLH ,150-300 unit subcutaneously.
The second Intervention group (n=70) received oral contraceptive, GnRH, rFSH 150-300 Unit subcutaneosly and 75 Unit of HMG

Sponsors

Vice Chancellor or Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged 20-35 years;Tubal or unexplained infertility, regular menstruation cycle between 21 and 35 days; Normal function of uterus according to hysterosalpingography; hysteroscopy or transvaginal ultrasonography; Normal ovaries according to transvaginal ultrasonography during past 6 months prior to study and compatible with normal adnexa and normal ovarian anatomy; Serum FSH level less than 8 IU/l. Exclusion Criteria: Patients with other ovulation disorders such as hypo and hyper-gonadotropic; hypo gonadism; hyper-prolactinemia; thyroid disorders; ovarian or adrenal neoplasms; Cushing syndrome; previous history of systemic diseases such as endocrine and metabolic disorders and a previous history of inappropriate ovarian response to stimulation with gonadotropins (poor responders), prior history of more than 3 unsuccessful IVF; any malformation of sexual organs were excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: two weeks after embryo transfers. Method of measurement: Blood test.;Clinical Pregnancy. Timepoint: three weeks after seeing sac fetus. Method of measurement: transvaginal sonography.;Live birth. Timepoint: after delivery. Method of measurement: Live birth.;Abortion. Timepoint: two weeks after embryo transfers. Method of measurement: transvaginal sonography.

Secondary

MeasureTime frame
Number of oocyte. Timepoint: six day after treatment. Method of measurement: Transvaginal sonography.;Number of embryo. Timepoint: one day after oocyte pick up. Method of measurement: See under a microscope by a specialist in embryology.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Farshbaf Taghinejad

School of Medicine, Tehran University of Medical Sciences.

mina.farshbaft@gmail.com+98 21 6658 1658

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026