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The effect of high-intensity interval training(HIIT) and quercetin supplementation on oxidative stress, level of concentric pathologic hypertrophy and cardiac function

The effect of high-intensity interval training(HIIT) and quercetin supplementation on oxidative stress, level of concentric pathologic hypertrophy and cardiac function in patients with hypertension and CAD after PCI.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160927030023N3
Enrollment
36
Registered
2020-02-20
Start date
2018-12-22
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hypertension. Condition 2: CAD. Essential (primary) hypertension Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Intervention group: 250 mg doses of 1 capsules of quercetin+ HIIT for 8 weeks. Intervention 2: Control group: 2 + placebo control group resistance training for 8 weeks. Intervention 3:

Sponsors

Shahid Rajaee Teacher Training University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: At least 2 and up to 4 weeks after angioplasty (drug stent only), Male 40-60 years old Systolic hypertension (SBP <130 mmHg <130 ) Mild to moderate congenital cardiac hypertrophy

Exclusion criteria

Exclusion criteria: Patients' non-adherence to exercise protocol Exercise outside the rehabilitation center Non-compliance with supplement use (less than 80% or less than 1 day) Changing health and abnormal change of medication People who have a history of kidney failure, heart attack or heart valve surgery, have aortic stenosis, dilated cardiomyopathy, and EF below 30%, are in frequent practice of PVC or AF. Leaving practice sessions over 1 week or more than 3 dispersed sessions

Design outcomes

Primary

MeasureTime frame
EF. Timepoint: Before and after 8 weeks. Method of measurement: Eco cardiography.;MDA. Timepoint: Before and after 8 weeks. Method of measurement: Elisa.;TAC. Timepoint: Before and after 8 weeks. Method of measurement: Elisa.;LVEDd. Timepoint: Before and after 8 weeks. Method of measurement: Eco cardiography.;PWDd. Timepoint: Before and after 8 weeks. Method of measurement: Eco cardiography.

Secondary

MeasureTime frame
Systolic blood pressure. Timepoint: Before and after 8 weeks. Method of measurement: Manometer.;Diastolic blood pressure. Timepoint: Before and after 8 weeks. Method of measurement: Manometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhalil Ullah Moonikh

Rajai Teacher Training University

kh.moonikh@srttu.edu+98 21 2297 0060

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026