xerostomia. Disturbances of salivary secretion
Conditions
Interventions
Intervention 1: intervention group:Modiff drug.the combination of Althea and Plantago psyllium and mallow.5 gram saschet. every 8 houres each saschet dissolve in 1 glass of water .drinl daily for 3mou
Treatment - Drugs
intervention group:Modiff drug.the combination of Althea and Plantago psyllium and mallow.5 gram saschet. every 8 houres each saschet dissolve in 1 glass of water .drinl daily for 3mounths
placebo group:each sachet contains 5 gram wheat flour plus food colouring produced by Magnolia company. every 8 houres each saschet dissolve in 1 glass of water .drinl daily for 3mounths
Sponsors
Salamat negar Hekmat pazhoohan corporation ofof Medical Science Traditional Medical School of Tehran
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criterias:xerostomia at least grade 2 based on Avraham Eisbruch trial's grading(grade1:no malfunction, grade 2:need to exess fluid to swallow, grade 3: changes in nutririon ,sleep,speech and other activities); taking more than 40gray radition to head and neck to be more than three major salivary glands in the radition field;age of 18 years and older; at least 3 mounths later than the end of the radation. Exclusion criteria:alcohol and other drugs consumption that affect salivary glands like anti depressant;history of connective tissue and collagen vascular diseases like sjogren, rheumatoid arthritis, lupus;systemic or local reccurents;need to prenteralnutrition hospitalsation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Saliva amount. Timepoint: 3times in 3 mountes intervals. Method of measurement: collecting saliva in 5 mintusein the 1 scaled test tube.;Quality of life. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare. | — |
Secondary
| Measure | Time frame |
|---|---|
| Constipation. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.;Skin dryness. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare.;Quality of sleep. Timepoint: 3times in 3 mountes intervals. Method of measurement: questionare. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeedeh Archang
Cancer Institue of Imam Khomeyni Hospital Complex
Outcome results
None listed