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Comparing effect of oxytocin versus oxytocin-propranolol combination on labor progression

Comparing effect of oxytocin versus oxytocin-propranolol combination on labor progression

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016092629983N1
Enrollment
130
Registered
2016-11-15
Start date
2016-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

]nduction and Promotion of labor. Spontaneous vertex delivery

Interventions

Intervention 1: Intervention group oxytocin with dose 2 mIU/min which increase every 15 min. Intervention 2: Intervention group oxytocin- propranolol, oxytocin with dose 2 mIU/min which increase every
Treatment - Drugs
Intervention group oxytocin with dose 2 mIU/min which increase every 15 min
Intervention group oxytocin- propranolol, oxytocin with dose 2 mIU/min which increase every 15 min and propranolol 2 mg/ml IV

Sponsors

Gorgan Congenital malformations research center, Golestan University of Medical Sciences,Gorgan, Ira
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: 37 to 41 weeks gestational age based on reliable LMP and ultrasound confirmation in the first quarter, also nuliparity; singleton, cephalic presentation;, intact membranes , bishop score equal to or less than 5. Exclusion criteria: CPD; any history of previous surgery on the uterus; fetal distress; the risk of macrosomia or polyhydramnius; SBP=100; PR=60; PR=120 min; any history of cardiopulmonary disease; known metabolic disease of mother or taking medicine for any illness in the mother.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The duration of phases of labor. Timepoint: Since the intervention untile delivery. Method of measurement: vaginal exam.

Secondary

MeasureTime frame
Neonate s Apgar. Timepoint: After Delivery. Method of measurement: According to the protocol.;Pregnancy ending in caesarean section. Timepoint: After the second period of injection. Method of measurement: Based on the indications for cesarean section.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Elaheh Amiri

Golestan University of Medical Sciences

dr_amiri_91@yahoo.com+98 17 3225 1391

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026