Thyroid nodule. Disorders of thyroid gland
Conditions
Interventions
Intervention 1: intervention group:using levothyroxine with therapeutic dose of 1.8 µg/kg, daily, for 24 months. Intervention 2: control group:using placebo half to one tablet, daily, for 24 months.
Treatment - Drugs
Placebo
intervention group:using levothyroxine with therapeutic dose of 1.8 µg/kg, daily, for 24 months
control group:using placebo half to one tablet, daily, for 24 months
Sponsors
Guilan University of Medical Sciences, Vice chancellor for research
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:patiens with single or multi thyroid nodules that have been proved to be benign with FNA Exclusion criteria:age under 20 and over 60; hypo or hyper thyroidism; history of using levothyroxine during past year; osteoporosis ; pregnancy; cardiovascular disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid nodule volume. Timepoint: beginning of assessment,6 months later after intervention , 12 months later ,18 months later , 24 months later. Method of measurement: ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| TSH. Timepoint: before intervention, 6 weeks later, then every 3 months. Method of measurement: laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAhmad Alizadeh
Razi hospital
Outcome results
None listed