Pneumonia. Pneumonia due to Streptococcus pneumoniae, Pneumonia due to Haemophilus influenzae, Bacterial pneumonia, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group will receive standardized extract containing 130 milligrams of poly phenol three times a day at 8 AM, 2 PM and 8 PM for one week. Intervention 2: Control group wil
Treatment - Drugs
Placebo
Intervention group will receive standardized extract containing 130 milligrams of poly phenol three times a day at 8 AM, 2 PM and 8 PM for one week
Control group will receive placebo three times a day at 8 AM, 2 PM and 8 PM for one week
Sponsors
Islamic Azad University of Pharmaceutical Science
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: ICU admission less than 1 week ; SIRS positive ; APACHE Score higherthan 10 ; Pneumonia diagnosis ; Tea consumption history Exclusion criteria : being NPO ; pregnancy ; age less than 18 years
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total anti-oxidant power. Timepoint: Day 0, 3, 7. Method of measurement: FRAP.;Total plasma thiol. Timepoint: Day 0, 3, 7. Method of measurement: Ellman method.;Interleukin 6. Timepoint: Day 0, 7. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lenth of stay. Timepoint: at the end of the study. Method of measurement: mathematical.;Mechanical ventilation days. Timepoint: at the end of the study. Method of measurement: mathematical.;APACHE II score. Timepoint: day 0,7. Method of measurement: medical calculator. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRamin Abrishami
Islamic Azad University of Pharmaceutical Sciences
Outcome results
None listed