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Effect of transdermal Estradiol gel compare Estradiol valerat on endometrial preparation in freeze embryo transfer cycle cycle

Evaluation the effect of Oestragel and Estradiol valerate on clinical pregnancy rate on patient that candidate for freeze embryo transfer cycle.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016092429951N1
Enrollment
100
Registered
2017-01-02
Start date
2015-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: freeze transfer embryo. Condition 2: preparation of Endometrium for freeze embryo transfer. Disease of the genitourinary system Disease of the genitourinary system

Interventions

Intervention 1: Intervention group:In group 2 (n=50 ) , patients received transdermal oestrogel 8mg in the first day of menstrual cycle until endometrial length greater than 8 mm, Then embr
Treatment - Drugs
Intervention group:In group 2 (n=50 ) , patients received transdermal oestrogel 8mg in the first day of menstrual cycle until endometrial length greater than 8 mm, Then embryo transfer were
Control group : group 1 (n=50) received of estradiol valerat tablet 8 mg per day from 1th day of menstrual until endometrial length greater than 8mm, Then embryo transfer were performed. Proge

Sponsors

Vice Chancellor for Research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: hyperstimulation in previous cycle and non- transfer in fresh cycle; premature menu pose; menu pose; patients who candidate for embryo and egg donation Exclusion criteria: hyper sensitivity to gonadotropin releasing hormone agonist; fresh cycle .

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Endometrial thickness. Timepoint: 13 th day of menstrual cycle. Method of measurement: Transvaginal sonography.

Primary

MeasureTime frame
Clinical Pregnancy. Timepoint: two week after embryo transfer. Method of measurement: Blood test for confirm of pregnancy with ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Kabodmehri

Reproductive Health Research Center

rk@tums.razi.ac.ir+98 21 6119 2049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026