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Ultrafiltration effect on coronary artery bypass surgery

Zero-balance ultrafiltration method to evaluate the effect on clinical outcomes in patients undergoing coronary artery bypass surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016092229914N1
Enrollment
75
Registered
2017-05-01
Start date
2016-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease. Atherosclerotic cardiovascular disease, so described

Interventions

Intervention 1: Hemofilter action in the intervention group since the beginning of cardiopulmonary bypass connected to the system and maintain the volume of the tank by adding intravenous normal sali
Treatment - Other
Hemofilter action in the intervention group since the beginning of cardiopulmonary bypass connected to the system and maintain the volume of the tank by adding intravenous normal saline or ringer on
In the control group there is

Sponsors

Vice CHancellor For Research, Iran university Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Non-inclusion criteria Liver failure as ((AST> 40 unit / L) and (ALT> 40 unit / L);A history of heart surgery;High serum creatinine1/5mg / dL; And patients who received the drug because before during 5 days acute renal failure have had severe narrowing of the carotid both carotid or one of them; Surgery emergency; IE; Ejection fraction of the left ventricle less than 30 percent of patients with Severe failure right ventricle Hemoglobin less than 10;Mass index BMI greater than 40;Benign and malignant cancers;Clamped aortic bypass for more than 120 minutes and 150 minutes; Pulmonary function test abnormal preoperative FEV1 <65 Exclusion criteria Prime 8/5000 Autologus do the opposite; Using the CUF; Using MUF; Patient died during surgery; Use of Intraoperative balloon pump;Use of ECMO; The need to stay open sternum after surgery; The patient needs cardiopulmonary resuscitation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cerebral oxygenation. Timepoint: 1.Preoperative2.Start operation3.Intraoperative4.Postoperative2. Method of measurement: Invos devices.;Arterial blood gases. Timepoint: Before surgery2.Start operation3.Intraoperative4.End the practice of5.6 hours after surgery. Method of measurement: Arterial blood gas measurement.;Liver enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory.;Kidney enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory.;Cardiac arrhythmia. Timepoint: Preoperative and postoperative. Method of measurement: ECG machine.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRobabeh KHalili

Iran University of Medical Sciences

robabekhalili64@gmail.com+98 88882885

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026