The effect of glutamine supplementation on serum levels of Adiponectine and TNFa after exhaustive exercise in young males

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016092129895N1

Enrollment

Registered

2016-10-13

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Young healthy males. Examination for participation in sport

Interventions

Intervention 1: Given 0.3 gr Glutamine in per Kgr weight of body with 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for intervention group. Intervention 2: Given 25 gr sweat an

Placebo

Given 0.3 gr Glutamine in per Kgr weight of body with 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for intervention group

Given 25 gr sweat and 250 cc water for 14 days and once exhaustive exercise for control group

Eligibility

Sex/Gender

Male

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Young healthy males with moderate physical activity in 18-30 years old. Exclusion criteria: Individuals with any diseases; smoking; alcoholism and other supplements consumption; having certain dietary; professional training; sedentary and having BMI over 25 and less than18.5 kg.m2

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Exhaustive exercise time. Timepoint: At the end of exercise. Method of measurement: With signs and symptoms of exhaustion.	—

Secondary

Measure	Time frame
Total cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;HDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;HsCRP. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Adiponectin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Height. Timepoint: At the beginning of intervention. Method of measurement: Stadiometers.;Malondialdehyde. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Weight. Timepoint: At the beginning of intervention. Method of measurement: Digital scales.;Total antioxidant capacity. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Tumor necrosis factor-alpha. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;LDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;Matrix metalloproteinase-2. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Matrix metalloproteinase-9. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Interlukine-6. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Leptin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Oxidated LDL. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.	—

Measure

Time frame

Total cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;HDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;HsCRP. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Adiponectin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Height. Timepoint: At the beginning of intervention. Method of measurement: Stadiometers.;Malondialdehyde. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Weight. Timepoint: At the beginning of intervention. Method of measurement: Digital scales.;Total antioxidant capacity. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Tumor necrosis factor-alpha. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;LDL-cholesterol. Timepoint: At the beginning of intervention, previous of exercise. Method of measurement: Spectrophotometry.;Matrix metalloproteinase-2. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Matrix metalloproteinase-9. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Interlukine-6. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Leptin. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Oxidated LDL. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Mollazadeh

Ardabil University of Medical Sciences

le.mollazadeh@arums.ac.ir+98 45 1383 1568

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026