Comparison of the effect of interferon alfa 2 b (IFN-a2b) drops with mitomycin c during surgery on pterygium recurrence in pterygium surgery

Comparison of the effect of interferon alfa 2 b (IFN-a2b) drops with mitomycin c during surgery on pterygium recurrence in pterygium surgery by Rotational conjunctival autograft method

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160919029871N5

Enrollment

Registered

2021-12-26

Start date

2021-12-22

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pterygium. Pterygium of eye

Interventions

Intervention 1: Intervention group: Intervention group: Aside from the topical Bethamethasone and Antibiotic drops the intervention group will receive topical drops of interferon alfa 2 b (IFN-a2b) dr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a Pterygium larger than 3 mm at horizontal width over the cornea on Slit-lamp exam who are candidates for surgery

Exclusion criteria

Exclusion criteria: Patients with previous pterygium recurrence, pseudo- Pterygium? Pregnant and breastfeeding mothers, systemic disease like diabetes and heart disease Ocular surface disease like keratitis or dry eye or conjunctivitis?Prior ocular surgery within 6 months Hypersensitivity to interferon alfa 2 b.

Design outcomes

Primary

Measure	Time frame
Clinical in?ammation grading and pterygium recurrence. Timepoint: Day 1, 3, 7, 30, 90 and 6 months after surgery. Method of measurement: Clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mitra Akbari

Rasht University of Medical Sciences

mitra.akbari20@gmail.com+98 13 3323 6886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026