Evaluation of topical cholestyramin in relieving pruritus and burning after ileostomy

Evaluation of cholestyramin 15% cream in relieving pruritus and burning after ileostomy: a randomized, double blind, placebo control clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201609153014N15

Enrollment

Registered

2017-01-02

Start date

2016-06-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Illeostomy. Colostomy and enterostomy malfunction

Interventions

Intervention 1: Intervention: Cholestyramin 15% cream, twice daily for 2 months. Intervention 2: Control: Cream without active ingredient, twice daily for 2 months.

Treatment - Drugs

Intervention: Cholestyramin 15% cream, twice daily for 2 months

Control: Cream without active ingredient, twice daily for 2 months

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidate for illeostomy Exclusion criteria: Hypersensitivity reaction to the product; Increasing irritation and inflammation after using product

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pruritus. Timepoint: 7th,14th,21th,28th day and two month after illeostomy. Method of measurement: Visual analog scale.	—

Secondary

Measure	Time frame
Side effects. Timepoint: 7th,14th, 21th, 28th day and two month after surgery. Method of measurement: Questionnarie.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shahram Ala

Mazandaran University of Medical Science, Faculty of Pharmacy

sala@mazums.ac.ir+98 11 3354 3083

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026