Diabetic nephropathy. Glomerular disorders in diabetes mellitus
Conditions
Interventions
Intervention 1: Calcitriol 0.25 mcg administered for 3 months for patients in intervention group. Intervention 2: placebo.
Sponsors
Vice Chancellor for Research of University of Medical Sciences and Health Services,Yazd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Type 2 diabetes concumption of ARB and ACE inhibitors for at least one year However, despite the above treatment, microalbuminuria still exists (30-300 mg of albumin after 8-12 hours of fasting, which is checked by the turbidimetry method)
Exclusion criteria
Exclusion criteria: type 1 diabetes blood pressure> 140/90 PTH>75 ng/d history of kidney stones or kidney stones during the study period hypercalcemi ( Ca > 10/3 mg/dl) calcitriol use or vitamin D albuminuria >300 mg/24hours acute liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mico-albuminuria. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;Fbs. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;HbA1c. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;TG. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;Total cholestrol. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;LDL. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling.;HDL. Timepoint: at baseline and three months after the initiation of trial. Method of measurement: Blood sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHemayati Roya
Yazd Diabetes Research Center
Outcome results
None listed