Comparison of Dexamethasone- Ketamine and Dexmedetomidine ?for prevention of postoperative nausea and vomiting during and ?after cesarean section under spinal anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016091320258N10

Enrollment

120

Registered

2016-11-08

Start date

2017-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean. Single delivery by caesarean section

Interventions

Intervention 1: We injected 20? milliliter normal saline in first group. Intervention 2: We injected 8 milligram of ?Dexamethasone in 20 ml of normal ??saline in second group. Intervention 3: We injec

Treatment - Drugs

We injected 20? milliliter normal saline in first group

We injected 8 milligram of ?Dexamethasone in 20 ml of normal ??saline in second group.

We injected ??0/5 milligram in Ketamine in 20 milliliter ?normal ?saline in 10 minute in third group.

We injected 1 microgram per ?kilogeram of Dexmedetomidine in ??20 milliliter of ?normal ?saline in 10 minute in fourth group.

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: single pregnancy; 18 -35 years; elective cesarean section; ASA ?I,II Exclusion criteria: general anesthesia; prescription drugs after delivery; body ?mass index more than 35; motion sickness; Intrauterine growth retardation; ?history of anti-nausea and vomiting 24 hours before surgery; history of ?gastrointestinal disease; history of allergy; Nausea and vomiting before ?clamping the umbilical cord; lack of patient satisfaction.?

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausa and vomitting. Timepoint: After clamping the umbilical cord ?. Method of measurement: Visual Analogue Scale.;Blood pressure. Timepoint: Every 5 minute to recovery. Method of measurement: Millimeter Hg.;Heart rate. Timepoint: Every 5 minute to recovery. Method of measurement: Count.;Oxygen saturation. Timepoint: Every 5 minute to recovery. Method of measurement: Percent.;Patient satisfaction ?. Timepoint: After recovery. Method of measurement: Visual Analogue Scale.;Total of dose of Metoclopramide. Timepoint: After recovery. Method of measurement: Miligeram.;Degree of patient peace ?. Timepoint: Before prescribe to after recovery. Method of measurement: Ramsay Scale? ?.	—

Measure

Time frame

Nausa and vomitting. Timepoint: After clamping the umbilical cord ?. Method of measurement: Visual Analogue Scale.;Blood pressure. Timepoint: Every 5 minute to recovery. Method of measurement: Millimeter Hg.;Heart rate. Timepoint: Every 5 minute to recovery. Method of measurement: Count.;Oxygen saturation. Timepoint: Every 5 minute to recovery. Method of measurement: Percent.;Patient satisfaction ?. Timepoint: After recovery. Method of measurement: Visual Analogue Scale.;Total of dose of Metoclopramide. Timepoint: After recovery. Method of measurement: Miligeram.;Degree of patient peace ?. Timepoint: Before prescribe to after recovery. Method of measurement: Ramsay Scale? ?.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNilufar Shams

Medicine department

alikamaliir@yahoo.com+98 86 3417 3638

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026