Condition 1: Non-insulin-dependent diabetes mellitus. Condition 2: Spouses. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged between 18-60 years old With clinically diagnosed type 2 diabetes for at least 6-month and maximum of 10 years With hemoglubin A1C lower than 8 percent Only take oral anti-hyperglycemic agents for the treatment have intention to enter the study and fill the informed consent
Exclusion criteria
Exclusion criteria: Being on insulin therapy History of known Cardiovascular Diseases (Coronary Artery Disease, Stroke, Congestive heart disease) Coronary artery bypass grafting (CABG) History of kidney or liver disease [alanine aminotransferase (ALT) and aspartate aminotransferase (AST) three times more than normal values] history of cancer Changing the dose of lipid lowering medications for at least 3 months prior starting the study being pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum high density lipoprotein cholesterol (HDL-C). Timepoint: start and the end of each intervention period. Method of measurement: Using Appropriate kits, by Alpha-Classic autoanalyzer.;Serum fasting blood sugar(FBS). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Serum low Density Lipoprotein cholesterol (LDL-C). Timepoint: start and the end of each intervention period. Method of measurement: Using Appropriate kits, by Alpha-Classic autoanalyzer.;Serum Total cholesterol. Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Serum triglyceride level (TG). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer. | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI(body mass index). Timepoint: entrance and start and the end of each intervention period. Method of measurement: kg/m2.;Body Fat percent. Timepoint: entrance and start and the end of each intervention period. Method of measurement: by body composition analyzer.;Muscle mass percent. Timepoint: entrance and start and the end of each intervention period. Method of measurement: by body composition analyzer.;Weight. Timepoint: entrance and start and the end of each intervention period. Method of measurement: by body Calibrated scale.;Blood pressure. Timepoint: entrance and start and the end of each intervention period. Method of measurement: by Barometer.;Insulin. Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate ELISA kit.;Lipoprotein(a). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Apo lipoprotein A (Apo A). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Apo lipoprotein B(Apo B). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Alkaline phosphatase ( ALP). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Alanine aminotransferase (ALT). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Aspartate aminotransferase (AST). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Gama glutamil transferase (GGT). Timepoint: start and the end of each intervention period. Method of measurement: using Appropriate kits, by Alpha-Classic autoanalyzer.;Urea. Timepoint: start and the end of each intervention peri | — |
Countries
Iran (Islamic Republic of)
Contacts
Nutrition and Food security Research Center, Faculty of Health, Shahid Sadoughi University of Medica