Obesity And Overweight. Obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention groups: receive 50000 IU vit D once in first week as a blues and 2000 IU vit D per day from second week and 0.5 to 1 kg per week weight lose for 8 weeks in obese and ove
Prevention
Placebo
Intervention groups: receive 50000 IU vit D once in first week as a blues and 2000 IU vit D per day from second week and 0.5 to 1 kg per week weight lose for 8 weeks in obese and over weight people
control group: receive placebo of vitamin D (edible paraffin) every week for 8 weeks in obese and over weight people undergoing low callorie diet.
Sponsors
Vice chancellor for research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age of 20-50; BMI= 25-40; don’t taking the glucose and lipid- lowering drugs; vitamin D deficiency; interesting in participation in research; without any metabolic disease; CHD; diabetes; without autoimmune disease; cancer; without infection disease in research; no smoking; no alcoholism; without immune system suppressor drugs 6 mounts before research; no menstrual bleeding; without any diet 3 mounts before research; no consumption vit D and antioxidant supplementation and multivitamin mineral during research; without use of medication affecting Vitamin D metabolism; without use of tanning bed during the study and 3 months before study initiation; without renal and hepatic diseases; women without polycystic ovary syndrome exclusion criteria: metabolic; CHD; autoimmune disease and cancer; infection disease in research; smoking; alcoholism; use of immune system suppressor drugs 6 mounts before research; menstrual bleeding; diet 3 mounts before research; consumption vit D supplementation and multivitamin mineral during research; use of medication affecting Vitamin D metabolism; use of tanning bed during the study and 3 months before study initiation; Having renal and hepatic diseases; women with polycystic ovary syndrome; no interesting for participation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PON 1, FFA. Timepoint: Before and after intervention. Method of measurement: ELIZA.;Apo B100, apo A1. Timepoint: Before and after intervention. Method of measurement: ELIZA.;DHEA, Insulin. Timepoint: Before and after intervention. Method of measurement: ELIZA.;Vitamin D. Timepoint: Before and after intervention. Method of measurement: ELIZA.;Fat Percent. Timepoint: Before and after intervention. Method of measurement: BIA method.;BMI. Timepoint: Before and after intervention. Method of measurement: Formula.;Waist circumference. Timepoint: Before and after intervention. Method of measurement: Meter.;Systolic blood pressure. Timepoint: Before and after intervention. Method of measurement: manometer.;Diastolic blood pressure. Timepoint: Before and after intervention. Method of measurement: manometer.;Nutritional status. Timepoint: Before and after intervention. Method of measurement: Measurement of energy and nutrients intake using 24-hour dietary recall method and anthropometric measurement using scale and stadiometer.;Exposure of sunlight. Timepoint: Before and after intervention. Method of measurement: Exposure of sinlights questionnaire.;Phisical Activity. Timepoint: Before and after intervention. Method of measurement: International phisical activity questionnair ( IPAQ). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Farzad Shidfar
Iran University of Medical Sciences, School of Public Health
Outcome results
None listed