Effectiveness of Cognitive Rehabilitation in Multiple Sclerosis.

Effectiveness of Cognitive rehabilitation on cognitive status (attention, memory, executive function) and quality of life in patients with multiple sclerosis: A randomized control clinical trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016090929714N1

Enrollment

Registered

2016-12-18

Start date

2016-10-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia in other specified diseases classified elsewher. Dementia (in): cerebral lipidosis, epilepsy, hepatolenticular degeneration, hypercalcaemia, hypothyroidism, acquired, intoxications, multiple sclerosis, neurosyphilis, niacin deficiency, polyarteritis nodosa, systemic lupus erythematosus, trypanosomiasis

Interventions

Intervention 1: Intervention group: 8 sessions of cognitive rehabilitation group therapy with focus on attention, memory and executive function, for a duration of 4 weeks, 2 sessions in each week, las

Rehabilitation

Intervention group: 8 sessions of cognitive rehabilitation group therapy with focus on attention, memory and executive function, for a duration of 4 weeks, 2 sessions in each week, lasts 45 to 60 mins

Control group: no intervention

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- At least 6 grade of school education; 2- Age between 18 to 45 years old; 3- Relapsing-Remitting multiple sclerosis; 4- Right dominance Exclusion criteria: 1- Multiple sclerosis attack in the recent 6 months; 2- Left dominance or ambidexterity; 3- Patients unwilling to participate in the survey; 4- Psychiatric debilitating illness; 5- Chronic psychiatric disease; 6- No motor deficit; 7- Pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Memory. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: ACE-R test.;Executive function. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: CFQ Quastinaire, WSCT test.;Attention. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: Reactio time, CPT test.	—

Measure

Time frame

Memory. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: ACE-R test.;Executive function. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: CFQ Quastinaire, WSCT test.;Attention. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: Reactio time, CPT test.

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Secondary

Measure	Time frame
Quality of life. Timepoint: before intervention- immediately after intervention- 3 months after intervention. Method of measurement: questionaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMani Arash

Shiraz University of Medical Sciences

mania@sums.ac.ir+98 71 3627 9319

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026