Sepsis. Sepsis, unspecified
Conditions
Interventions
Intervention 1: Intervention group : These patients will received 1 milliliter vitamin D (300000 IU) ( institut Pasteur.Tehran .Iran ) , single dose, Intramuscularly. Intervention 2: Control group
Treatment - Drugs
Placebo
Control group : These patients will received 1 ml intramuscular, single dose of normal saline as placebo.
Intervention group : These patients will received 1 milliliter vitamin D (300000 IU) ( institut Pasteur.Tehran .Iran ) , single dose, Intramuscularly.
Sponsors
Arak University of Medical Sciences, Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age greater than 18 years old; Sepsis diagnosis and infection source; Patients satisfaction Exclusion criteria: Calcium level greater than or equal to 10 mg/dl; Vitamin D intake during 7 days ago; History of parathyroid diseases; Metabolic bone disease; Sarcoidosis; End stage renal disease (ESRD); Impending death; Pregnancy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Ca level. Timepoint: 3 months after injection. Method of measurement: mg/dl.;Serum Vitamin D level. Timepoint: 3 months after injection. Method of measurement: mg/dl.;Tumor necrosis factor alpha. Timepoint: 3 months after injection. Method of measurement: ELISA.;Interleukin 10. Timepoint: 3 months after injection. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Abolfazl Jokar
Vali-e-Asr hospital
Outcome results
None listed