Intrauterine infusion of autologous platelet rich plasma (PRP) on women with repeated frozen thawed cycles failure

Clinical trail of comparison of pregnancy outcome in women with history of repeated implantation failure after intrauterine infusion of autologous platelet rich plasma (PRP) and women without intervention undergoing frozen thawed cycles

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016090728950N3

Enrollment

Registered

2016-11-26

Start date

2016-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female infertility. female infertility unspecified

Interventions

Intervention 1: Intervention group:In 2nd day of cycle the patients undergo a basic trans vaginal sonography. For all the women who enter in frozen thawed cycles, estradiol tablet 2mg three times dail

Treatment - Drugs

Intervention group:In 2nd day of cycle the patients undergo a basic trans vaginal sonography. For all the women who enter in frozen thawed cycles, estradiol tablet 2mg three times daily is initiated.

Control group: In 2nd day of cycle the patients undergo a basic trans vaginal sonography. For all the women who enter in frozen thawed cycles, estradiol tablet 2mg three times daily is initiated. In

Eligibility

Sex/Gender

Female

Age

18 Years to 42 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: women undergoing frozen thawed cycles; history of 2 or more history of implantation failure; age between 18 to 42 exclusion criteria: hematological and immunological disorders; hormonal disorders; chromosomal and genetic abnormalities; uterine abnormalities (congenital or acquired)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: serum pregnancy test.;Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: trans vaginal sonograghy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Nosrat Neghab

Yazd Research and Clinical Center for Infertility Shahid Sadoughi University of Medical Sciences

nosrat20@yahoo.com; nosratneghab@ssu.ac.ir+98 35 1824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026