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Effect of oral and vaginal administration probiotic in treatment of women with vaginal candidiasis

Effect of oral and vaginal administration probiotic in treatment of women with vaginal candidiasis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016090529710N1
Enrollment
80
Registered
2016-09-30
Start date
2016-07-20
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vulvovaginal Candidiasis. Candidiasis of vulva and vagina

Interventions

Intervention 1: Oral Fluconazol treatment with Oral probiotic capsules containing Lactobacillus acidophilus,Lactobacillus plantarum,Lactobacillus fermentum, Lactobacillus gasseri 1×10 9 colony are k

Sponsors

Kashan University of Medical Scinces and Health Services
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: married women aged 18-45 years old none pregnant absence of menstruation at the time of attendance not using vaginal medications, antibiotics , immonosupressive drugs and exogenous hormones such as oral contraceptives since 2 weeks before starting the research; not having intercourse or using vaginal douche within the last 24hours absence of any diagnose medical disease such as diabetis and other auto immune diseases, by asking the patient not having intercourse or using vaginal douche within the last 24 hours verification of vulvovaginal candidiasis resulted clinical symptoms and KOH positive smear and culture

Exclusion criteria

Exclusion criteria: allergic reactions to fluconazole, lactovag and lactofem pregnancy during therapy compulsion to use antibiotics or other anti fungal drugs.

Design outcomes

Primary

MeasureTime frame
Vaginal candidiasis symptoms. Timepoint: 35-30 days after starting probiotic or placebo treatment. Method of measurement: questionnaire.

Secondary

MeasureTime frame
Dirct smear and Culture. Timepoint: 30-30 days after starting treatment with fluconazole and probiotic or placebo. Method of measurement: culture and direct smear.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Nazeri

Department of Medical Parasitology and Mycology, Medical faculty, kashan university of medical scien

nazeri_me@kaums.ac.ir+98 31 5554 1112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026