Ibuprofen effect of postoperative pain management

Comparison of the effects of intravenous ibuprofen and pump pain with pump pain alone on postoperative pain in patients undergoing open appendectomy and inguinal hernia: a clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201608284131N3

Enrollment

Registered

2016-09-17

Start date

2016-09-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Open appendectomy. Condition 2: inguinal hernia. Acute appendicitis, other and unspecified, Other appendicitis Unilateral or unspecified inguinal hernia, without obstruction or gangrene

Interventions

Intervention 1: Intervention group: 400 mg ibuprofen intravenous injection in recovery which will be repeated on hours 1, 6, 12, 18 after surgery in addition to 15 ug/ml fentanyl pain pump. Interventi

Treatment - Drugs

Intervention group: 400 mg ibuprofen intravenous injection in recovery which will be repeated on hours 1, 6, 12, 18 after surgery in addition to 15 ug/ml fentanyl pain pump

Control group: bolus 15 ug/ml fentanyl pain pump

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients aged 20-60 years; candidate for open appendectomy or inguinal hernioplasty surgery. Exclusion criteria: underlying disease; gastrointestinal disease; opioid allergy; NSAID allergy; drug addiction, refusal of patients to consent for participating in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1, 6, 12, 18, and 24 hours after surgery. Method of measurement: Visual Analog Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. AmirAhmad Arabzadeh

Ardabil University Of Medical Sciences

a.sharghi@arums.ac.ir+98 45 3351 3777

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026