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Comparison of two different doses of thiopental sodium in elective cesarean section (C/S) under general anesthesia on depth of anesthesia with Isolated Forearm Technique (IFT) and on neonatal neurobehavioral test

Comparison of two different doses of thiopental sodium in elective cesarean section (C/S) under general anesthesia on depth of anesthesia with Isolated Forearm Technique (IFT) and on neonatal neurobehavioral test

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016082819470N45
Enrollment
80
Registered
2017-07-28
Start date
2017-08-25
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caesarean section. Delivery by elective caesarean section

Interventions

Intervention 1: Group one: Anesthesia will induce with administration of Thiopental (5 mg / kg) in group one and Scholine (2 mg / kg) will maintain with 50% N2O, O2, Sevoflurane and by N2O 50%, O2, se

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Aged between 15-50 pregnant women undergoing cesarean section ASA I-II

Exclusion criteria

Exclusion criteria: Patients who are not properly cooperate Prior use of sulfate MgSO4 Mental disorders History of previous awareness during general anesthesia Taking blood pressure medication or vasodilators or vasodepressor and human stimulant or psychotropic drugs Neuromuscular diseases Opium addiction Fetal abnormalities by ultrasonography

Design outcomes

Primary

MeasureTime frame
To determine the depth of the anesthesia by Sodium Thiopental and Propofol as an induction anesthetic. Timepoint: at baseline, Induction of anesthesia, laryngoscopy and intubation, Skin incision, opening the peritoneum, Uterine incision, uterine retraction, childbirth, Uterine closure, tying the layers under the skin, Subcutaneous closures, at the start of skin closure,2 minutes after skin closure, eye opening and extubation. Method of measurement: Bispectral index (BIS) and Isolated forearm technique (IFT.

Secondary

MeasureTime frame
Neonate Apgar. Timepoint: at 0, 5, and 20 minutes after birth. Method of measurement: Apgar score.;Neurobehavioral test. Timepoint: 20 minutes after birth. Method of measurement: Neurobehavioral test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Mirhadi

Shiraz University of Medical Sciences

fateme.mirhadi@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026