Comparison of depth of anesthesia in induction with sodium thiopental & propofol in elective cesarean section by BIS, IFT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016082819470N44

Enrollment

Registered

2016-12-21

Start date

2016-11-10

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caesarean section. Delivery by elective caesarean section

Interventions

Intervention 1: Group T: Anesthesia will induce by rapid sequence method with administration of Thiopental (5-4 mg / kg) in group T and Scholine (2 mg / kg) and cricoid pressure. Anesthesia until the

Treatment - Drugs

Group T: Anesthesia will induce by rapid sequence method with administration of Thiopental (5-4 mg / kg) in group T and Scholine (2 mg / kg) and cricoid pressure. Anesthesia until the birth will maint

Group P: Anesthesia will induce by rapid sequence method with administration of Propofol (2.5-2 mg / kg) in group P and Scholine (2 mg / kg) and cricoid pressure. Anesthesia until the birth will maint

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: 90 pregnant women (ASA I- II) who are under general anesthesia for elective cesarean section. Exclusion criteria: Patients who are not properly cooperate; patients who received magnesium sulfate MgSO4 before the study; mental disorders; Patients who have a history of previous awareness during general anesthesia, patients who take blood pressure medication or patients who require the use of vasodilators or vasodepressor drugs; patients who consume human stimulant or psychotropic drugs; mothers with multiple gestation or preterm labor; fetal distress, patients with neuromuscular diseases, opium addicts; history of multiple drug allergies or sensitivity to anesthetics; patients with bradycardia and heart block.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To determine the depth of the anesthesia bySodium Thiopental and Propofol as an induction anesthetic. Timepoint: at baseline, Induction of anesthesia, laryngoscopy and intubation, Skin incision, opening the peritoneum, Uterine incision, childbirth Uterine closure, , tying the layers under the skin, Subcutaneous closures, skin closure, turn off the gas anesthesia, eye opening and extubation. Method of measurement: bispectral index (BIS) and Isolated forearm technique (IFT).	—

Measure

Time frame

To determine the depth of the anesthesia bySodium Thiopental and Propofol as an induction anesthetic. Timepoint: at baseline, Induction of anesthesia, laryngoscopy and intubation, Skin incision, opening the peritoneum, Uterine incision, childbirth Uterine closure, , tying the layers under the skin, Subcutaneous closures, skin closure, turn off the gas anesthesia, eye opening and extubation. Method of measurement: bispectral index (BIS) and Isolated forearm technique (IFT).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Beihaghi

Shiraz University of Medical Sciences

beihaghim@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026