Effects of using low-dosage Imipramine and normal-dosage Desmopressin on nocturnal enuresis in children

Clinical trial of Effects of using low-dosage Imipramine and Desmopressin with normal dosage on nocturnal enuresis in children with a resistance against Desmopressin

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016082129459N1

Enrollment

Registered

2017-09-03

Start date

2016-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

enuresis. Unspecified urinary incontinence

Interventions

Intervention 1: Intervention group: Prescribed Desmopressin and 5 mg of Imipramine. Intervention 2: Control group: Prescribed Desmopressin.

Treatment - Drugs

Intervention group: Prescribed Desmopressin and 5 mg of Imipramine

Control group: Prescribed Desmopressin

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: primary nocturnal enuresis with single symptom; being of above 6 age; not having a kidney disorder; not having neurogenic bladder dysfunction; not being treated after using Desmopressin for one month. Exclusion criteria: drug side effects; not completing the treatment period; allergy to Imipramine; suffering from heart disorder; suffering from heart arrhythmia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bed wetting. Timepoint: Number of not bed wetting of the patient will be evaluated at baseline, 2 weeks later, 1 month later and then monthly until 6 months. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Anoosh Azarfar

Mashhad University of Medical Sciences

azarfara@mums.ac.ir+98 51 3726 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026