Facial skin wrinkles.
Conditions
Interventions
Intervention 1: In 45 to 75 years old patients with mild to moderate facial skin wrinkles, a half-face is subjected to a microneedling monthly up to three time and Its efficacy and safety are examined
Sponsors
Deputy of Research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age 45 to 75 Mild to moderate wrinkling on the face
Exclusion criteria
Exclusion criteria: Pregnant or breast feed History of cuagulopathy disorder or drug Facial active Infection Inability to fallow up visit connective tissue disorder History of skin cancer on face Unrealistic expectation Cosmetic procedures performed on the face in the last 6 month Fitzpatrick skin phototype >III Sensitivity to lidocain Use isotretinoin in the last 6 month History of keloid Use photosensitive drug such gold, tetracyclin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss. Timepoint: Before each treatment session and then after three month of treatment. Method of measurement: Measurement of skin biophysical properties by MPA-9 device.;Skin hydration. Timepoint: Before each treatment session and then after three month of treatment. Method of measurement: By dermatologist and using MPA-9 device.;Patient satisfaction. Timepoint: Before each treatment session monthly and then after three month of treatment. Method of measurement: Asking the patient.;Downtime. Timepoint: Before tretment every month and then after three month of treatment. Method of measurement: By dermatologist.;Clinical assessment of improvement. Timepoint: Before treatment every month and then after three month of treatment. Method of measurement: By dermatologist by comparing the patient's pictures.;Skin resonance time. Timepoint: Before treatment every month and then after three month of treatment. Method of measurement: By dermatologist and using reviscometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before esch treatment session monthly. Method of measurement: Asking the patient.;Burning. Timepoint: Before esch treatment session. Method of measurement: Asking the patient.;Erythema. Timepoint: Before esch treatment session. Method of measurement: Asking the patient.;Edema. Timepoint: Before esch treatment session. Method of measurement: Asking the patient.;Bulla formation. Timepoint: Before esch treatment session. Method of measurement: Asking the patient.;Bleeding. Timepoint: Before esch treatment session. Method of measurement: Asking the patient.;Dispigmentation. Timepoint: Before esch treatment session. Method of measurement: Asking the patient and by dermatologist.;Scar formation. Timepoint: Before esch treatment session. Method of measurement: Asking the patient and by dermatologist.;Skin atrophia. Timepoint: Before esch treatment session. Method of measurement: Asking the patient and by dermatologist.;Crust formation. Timepoint: Before esch treatment session. Method of measurement: Asking the patient and by dermatologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehnaz Hamedani
Skin Research Center of Shahid Beheshti University
Outcome results
None listed