comparing infusion of dexmedetomidin versus midazolam in patients admitted to intensive care unit

comparing longterm infusion of dexmedetomidin versus midazolam in mechanically ventilated patients admitted to intensive care unit

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201608192582N16

Enrollment

Registered

2016-11-08

Start date

2016-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unconsciousness. Disorder of central nervous system, unspecified

Interventions

Intervention 1: intervention group dexmedetomidine 0.4-0.8 µg/kg/h. Intervention 2: control group Midazolam 0.02-0.04 mg/kg.

Treatment - Drugs

intervention group dexmedetomidine 0.4-0.8 µg/kg/h

control group Midazolam 0.02-0.04 mg/kg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria: all patients with more than 18 years old who need to be admitted to ICU and ungergone mechanical ventilation exclusion criteria: allergy to recital drug; needing the infusion of both drugs;resistant to treatment hypotention; pregnancy or lactation; addiction history; CNS disease; dialysis history; hepatic function disorder; EF<30%

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Duration of mechanical ventilation. Timepoint: Daily. Method of measurement: counting the days under mechanical ventilation.	—

Secondary

Measure	Time frame
ICU length of stay. Timepoint: daily. Method of measurement: counting days of ICU stay.;Mortality. Timepoint: daily. Method of measurement: counting mortality.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNina Pilevar

Tabriz University of Medical Sciences

ninapilevar@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026