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Sedative and anesthetic effect of hypnotism versus propofol and dexmedetomidine and component of midazolam-fentanyl in aware and awake patient in ICU ward

Sedative and anesthetic effect of hypnotism versus acetaminophen, methadone and fentanyl in aware and awake patient in ICU ward: a single blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201608189014N110
Enrollment
96
Registered
2016-08-26
Start date
2016-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head injury. Superficial injury of head

Interventions

Intervention 1: hypnotism for an hour three times a day for 24 hours. Intervention 2: Control group 1: Acetaminophen 1 g intravenous every 6 hours for 24 hours. Intervention 3: Control group 2: Methad
Treatment - Other
Treatment - Drugs
hypnotism for an hour three times a day for 24 hours
Control group 1: Acetaminophen 1 g intravenous every 6 hours for 24 hours.
Control group 2: Methadone 2.5 mg subcutaneous every 8 hours for 24 hours.
Control group 3: Infusion of fentanyl 75 mg every 6 hours for 24 hours.

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age of 18 to 50 years; literate at least diploma; need mechanical ventilation with any reason. Exclusion criteria: consciousness disorder; acid-base disorder; psychiatric disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Assessing agitation. Timepoint: before intervention and 20, 40, 60 min and 1, 2, 6, 12, and 24 hours after intervention. Method of measurement: through physical examination.;Assessing pain. Timepoint: before intervention and 20, 40, 60 min and 1, 2, 6, 12, and 24 hours after intervention. Method of measurement: using VAS scale.

Secondary

MeasureTime frame
Assessing adverse effect (hypotension, apnea, bradycardia). Timepoint: 20, 40, 60 min and 1, 2, 6, 12, and 24 hours after intervention. Method of measurement: through physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Dori

Besat Hospital

9188170759+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026