Effect of Ephedrine and Ondansetron on Hypotension after Spinal Anesthesia

Comparison of the Effect of Ephedrine and Ondansetron on Spinal induced Hypotension Cesarean Section

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160818029414N5

Enrollment

165

Registered

2019-10-12

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after Spinal Anesthesia. Other complications of spinal and epidural anesthesia during labor and delivery

Interventions

Intervention 1: Intervention group: Ephedrine Group: Five minutes before the Spinal Anesthesia, two ml solution containing 10 mg ephedrine is given intravenously. Intervention 2: Intervention group: o

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 18-45 year ASA I,II Elective Cesarean section under Spinal Anesthesia

Exclusion criteria

Exclusion criteria: Patient dissatisfaction Infection at the spinal needle insertion site High intracranial pressure Coagulation Disorders A history of allergy to local anesthetics Heart, kidney, liver disease

Design outcomes

Primary

Measure	Time frame
Hypotension. Timepoint: Blood pressure measurement at the beginning of the Study and immediately after the Spinal Anesthesia, every three minutes to 15 minutes and then every five minutes until the End of the Operation. Method of measurement: Blood pressure Device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Mahmoodi koli

Zanjan University of Medical Sciences

Rashtchi@zums.ac.ir+98 25 3289 2188

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026