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Safety and efficacy of venous Paracetamol with venous Ibubrofen in treatment of Patent ductus arteriosus (PDA) among premature Neonates Hospitalized in NICU, Zanjan Ayatollah Musavi Hospital in 2016- 2017

Safety and efficacy of venous Paracetamol with venous Ibubrofen in treatment of Patent ductus arteriosus (PDA) among premature Neonates Hospitalized in NICU, Zanjan Ayatollah Musavi Hospital in 2016- 2017

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016081729404N1
Enrollment
30
Registered
2017-05-09
Start date
2017-03-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent ductus arteriosus (PDA). Patent ductus arteriosus

Interventions

Intervention 1: 15 infants receive Ibuprofen whit dose of 10 mg/kg/stat in the first day and 5 mg/kg/stat in the following second and third days. Intervention 2: 15 infants recieve Acetaminophen IV 15
Treatment - Drugs
15 infants receive Ibuprofen whit dose of 10 mg/kg/stat in the first day and 5 mg/kg/stat in the following second and third days.
15 infants recieve Acetaminophen IV 15 mg/kg/ every six hours for three days

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 3 Days

Inclusion criteria

Inclusion criteria: Neonate with 34 week age and less with PDA diagonsis by echocardiography.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
PDA size. Timepoint: PDA size befor and after treatment messured with echocardiography by pediatric cardiologist. Method of measurement: According to the disease severity and echocardiography results,Patient's PDA will be examined before and after treatment by pediatric cardiologis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abolfazl Ebadi

Zanjan University of Medical Sciences

a.ebadi2016@gmail.com+98 24 3313 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026