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Effectiveness of High-Flow Oxygen Therapy on clinical and spirometry findings in Acute Exacerbation of Asthma

Effectiveness of High-Flow Oxygen Therapy on clinical and spirometry findings in Acute Exacerbation of Asthma

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016081727929N2
Enrollment
Unknown
Registered
2016-09-10
Start date
2016-08-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute asthma. Acute severe Asthma

Interventions

Intervention 1: Control group: oxygen therapy with low flow (less than 10 liters per minute). Intervention 2: The intervention group received high-flow oxygen (between 10 to 50 liters per minute).
Treatment - Devices
Control group: oxygen therapy with low flow (less than 10 liters per minute)
The intervention group received high-flow oxygen (between 10 to 50 liters per minute)

Sponsors

Vice-Chancellor in Research Affairs shahid Beheshti university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Admission criteria: a history of asthma; aged between 18 and 65 years; no history of smoking; no pregnancy; no history of occupational asthma Exclusion criteria: critically ill patients requiring intensive care unit (life-threatening asthma); infiltrates on chest x-ray ; Hypercapnic respiratory failure

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Respiratory rate. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Examination.;Dyspnea score. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Borg scale.;Arterial oxygen saturation. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Arterial blood gas analysis.

Secondary

MeasureTime frame
Peak expiratory flow. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: peak flowmeter.;Forced expiratory volume in 1st second. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: spirometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSharareh Raeisi

National research institute of tuberculosis and lung diseases

shraeisi86@gmail.com+98 21 2712 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026