Comparison of pregnancy rate between fresh and frozen embryo transfer cycles in women with endometriosis

Clinical trial comparing pregnancy rate between fresh and frozen embryo transfer cycles in women with endometriosis: a pilot Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201608171141N21

Enrollment

Registered

2016-08-26

Start date

2014-01-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis of ovary. Endometriosis of ovary

Interventions

Intervention 1: Intervention/ Control: In the intervention group? embryos will be frozen for 2 months. Gonadotropin also is used for 2 months in order to prepare the endometrium. Then hormonal replace

Treatment - Other

Intervention/ Control: In the intervention group? embryos will be frozen for 2 months. Gonadotropin also is used for 2 months in order to prepare the endometrium. Then hormonal replacement therapy wi

Intervention/ Control: In control group, the fresh embryos will be transferred.

Eligibility

Sex/Gender

Female

Age

No minimum to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: infertile patients with endometriosis; age = 35 years; at least one endometrioma diagnosed by sonography or confirmed by laparoscopy; history of one failed in vitro fertilization failure (IVF). Exclusion criteria: women with well-known predisposing factors for implantation failure such as thrombophilia, underlying immune conditions, uterine malformation (i.e. didelphys, septate, bicornuate or hypoplastic uterus); parental chromosomal abnormalities; severe male factor infertility; cancelled cycles which did not result in embryo transfers; women with frozen embryos in which their cycles had been canceled due to thin endometrial thickness.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate. Timepoint: 4-6 weeks after embryos transfer (ET). Method of measurement: Vaginal sonography.	—

Secondary

Measure	Time frame
Implantation rate. Timepoint: 4-6 weeks after embryos transfer (ET). Method of measurement: Vaginal sonography.;Ongoing pregnancy rate. Timepoint: Pregnancy after 12 weeks of gestation. Method of measurement: Vaginal sonography.;Miscarriage rate. Timepoint: Abortion before 12 weeks of gestation. Method of measurement: Vaginal sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNadia Jahangiri

Royan Institute

tmadani@royaninstitute.org+98 21 2356 2645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026