intraocular pressure. Glaucoma secondary to drugs
Conditions
Interventions
Intervention 1: control group:
Another eye of each patient was received Flourometholone 0.1% four times a day for the first month, then three times a day for the second month and two times a day for t
Treatment - Drugs
control group:
Another eye of each patient was received Flourometholone 0.1% four times a day for the first month, then three times a day for the second month and two times a day for the third month
intervention group:
Each patient was randomly allocated to receive loteprednol 0.5% in one eye four times a day for the first month, then three times a day for the second month and two times a day
Sponsors
Vice Chancellor Of Research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age more than 18 years; stable refraction for at least 12 month with myopia between -8.0 to -1.0 Diopters and astigmatism less than 4.0 Diopters; normal eye examination (except refractive error); corrected distance visual acuity (CDVA) of 20/20; no history of systemic or autoimmune disease or receiving immunosuppressive treatment; neither pregnant nor breast feeder; using no topical ophthalmic medication; have no contraindication for PRK. Exclusion criteria: Patients were unable to return for follow-up or needed to increase drug dosage for any reason; patients who did not follow the instructions correctly; patients with anisometropia (more than 1 diopter) or significant pre-operative central corneal thickness difference between two eyes (more than 20 µm); those who received MMC just in one eye; patients with postoperative complications like keratitis.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure post photorefractive keratectomy. Timepoint: pre operation and 1,2,3 month post op. Method of measurement: Intraocular pressure was measured over central cornea by Goldmann applanation tonometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity. Timepoint: pre operative and 1,2,3 month post operatively. Method of measurement: Snellen chart.;Corneal haze. Timepoint: 3 month post operatively. Method of measurement: slit lamp examination.;Ocular surface side effects related to topical drugs including eye redness and eye discomfort. Timepoint: 3 month post operatively. Method of measurement: question. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahba Fekri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed