Congenital heart disease. Other congenital malformations of heart
Conditions
Interventions
Intervention 1: In dexmedetomidine group apart from common drugs used to manage anesthesia and pulmonary hypertension in patients with severe pulmonary hypertension like Milrinone and Sildenafil, dexm
Treatment - Drugs
Placebo
In the control group apart from common drugs used to manage anesthesia and pulmonary hypertension in patients with severe pulmonary hypertension like Milrinone and Sildenafil, Dexmedetomidine was not
In dexmedetomidine group apart from common drugs used to manage anesthesia and pulmonary hypertension in patients with severe pulmonary hypertension like Milrinone and Sildenafil, dexmedetomidine bega
Sponsors
Vice Chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All children under one year old undergoing elective surgery and have severe pulmonary hypertension and left to right shunt. Exclusion criteria: severe hepatic failure, renal failure (Cr =1 / 5); heart block; primary hypotension, bradycardia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arrhythmias. Timepoint: At 0,6,12, 24, 48, 72hours during surgery and after surgery in the ICU. Method of measurement: EKG monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary artery pressure. Timepoint: After surgery and after pulmonary artery catheter insertion in the intensive care unit. Method of measurement: pulmonary artery catheter.;Patient's extubation time. Timepoint: After transferring patient to the intensive care unit. Method of measurement: observasion. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahador Azizi
Shiraz University of Medical Sciences
Outcome results
None listed