diabetic retinopathy. Diabetic retinopathy
Conditions
Interventions
Intervention 1: Intervention group:The patients in this group receive topical Interferon alpha 2 b with dosage of 1 million unit per milliliter in the same container of placebo,4 times a day. one mill
Treatment - Drugs
Intervention group:The patients in this group receive topical Interferon alpha 2 b with dosage of 1 million unit per milliliter in the same container of placebo,4 times a day. one milliliter of Interf
Control group: The patients in this group receive artificial tear as placebo four times a day for 4 weeks and are examined on week 2,4 and 8 during study.
Sponsors
Vice chancellor for research of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: patient with diabetic macular edema. Exclusion criteria: patients with positive history of radiotherapy or treatment with immunosuppressive agents; patients with malignancy or who have undergone organ transplant; patients with previous ocular vascular accident; patients who have had cataract surgery in the past 3 months.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macular thickness. Timepoint: before intervention, 4 wks after start of intervention,4 wks after the end of intervention. Method of measurement: hidelberg OCT.;Visual acuity. Timepoint: before intervention, 4 wks after start of intervention. Method of measurement: snellen chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Leakage on fluorescein angiography. Timepoint: before intervention, 4 wks after start of intervention. Method of measurement: fluoresceine angiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAidin Meshksar
Shiraz University of Medical Sciences
Outcome results
None listed