Diseases of the genitourinary system. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: Intrauterine infusion of 0.5 CC of autologus platelet-rich plasma (has 4-6 times platelet concentration rather than peripheral blood by IUI catheter(Takvin company,
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women aged between 20-40 years BMI Between 20-30 kg/m2 Freez embryo transfer Prior failed embryo transfer cycle due to thin endometrium endometrial line below 7 on day 10 of cycle without endometrial pathology on hystrosalpingography or hysteroscopy
Exclusion criteria
Exclusion criteria: Abnormal uterine form conture on hystrosalpingography or hysteroscopy Hematologic disease Hormonal disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in endometrial thickness rate. Timepoint: 48 hours after intrauterine injections of platelet-rich plasma. Method of measurement: Ultrasound.;Clinical pregnancy rate. Timepoint: Forth weeks after embryo transfer. Method of measurement: Ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Miscarriage rates. Timepoint: Till twenty weeks after embryo transfer. Method of measurement: Questionnare.;Chemical pregnancy rate. Timepoint: Two weeks after embryo transfer. Method of measurement: B-HCG Kit.;Implantation rate. Timepoint: Forth weeks after embryo transfer. Method of measurement: Questionare. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Zamaniyan
Sari University of Medical Sciences
Outcome results
None listed