Diseases of the genitourinary system. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: Use of GnRH Agonist ampule (Variopeptil, 0.1 mg, SC, varian farmed, Iran) 0.2mg plus HCG (Choriomon ,5000 IU , IM, IBSA company , Switzerland) on HCG injection day.
Sponsors
Vice chancellor of Mazandaran University of Medical Science.
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Infertile women aged 20 to 45 years Normal hysterosalpingography AMH levels < 1.5 ng/ml Antral follicular counts (AFC) < 7 in both ovaries Prior less than three failed in vitro fertilization cycles
Exclusion criteria
Exclusion criteria: Normal ovarian response in ovulatory cycles or in vitro fertilization cycles
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate. Timepoint: Forth weeks after embryo transfer. Method of measurement: Utrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oocyte recovery rate. Timepoint: 48 hours after HCG injection. Method of measurement: Observation by microscopy.;Embryo rate. Timepoint: three days after oocyte recovery. Method of measurement: Observation by microscopy.;Miscarriage rate. Timepoint: Till twenty weeks after embryo transfer. Method of measurement: Ultrasound.;Oocyte quality. Timepoint: On oocyte recovery rate. Method of measurement: Observation by microscopy. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Zamaniyan
Mazandaran University of Medical Sciences
Outcome results
None listed