Infertility. Female infertility of uterine origin
Conditions
Interventions
Intervention 1: Intervention group :Intrauterine injection of 0.5 cc of autologous platelet-rich plasma (with a platelet concentration 4 to 6 times higher than peripheral blood) using an IUI catheter
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: The patient has had two or more failures in the process of new assisted reproductive technologies. Women undergoing ICSI cycles with frozen embryo transfer. Age 20 to 40 years. Endometrium with a minimum thickness of 7 millimeters at the time of embryo transfer preparation. Informed consent for participation in the study from the patient and spouse.
Exclusion criteria
Exclusion criteria: The presence of uterine abnormalities (such as large fibroids, polyps, uterine septum). Uncontrolled chronic systemic diseases (such as diabetes, high blood pressure). Blood or immunological diseases History of allergy or sensitivity to plasma products. Use of anticoagulant medications or bleeding disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy event. Timepoint: 14 days after embryo transfer. Method of measurement: Serum ß-hCG blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzia Zamanian
Mazandaran University of Medical Sciences
Outcome results
None listed