Cystoid macular edema. Other specified retinal disorders
Conditions
Interventions
Intervention 1: Intervention group : In this group, prostaglandin analogue (Latanaprost eye drop) is discontinued immediately after cataract surgery for 3 months and replaced with other antiglaucoma a
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Glaucoma patients with 18 years old or more Treating with topical latanoprost 0.005% eye drop at least for 6 months with or without other antiglaucoma topical agents Who needed cataract surgery (phacoemulsification)
Exclusion criteria
Exclusion criteria: History of any intraocular surgery, intravitreal injections, or retinal laser History of trauma Non-glaucomatous optic neuropathy High myopia History of diabetic retinopathy, any age-related macular degeneration (AMD), uveitis, retinal detachment (RD), epiretinal membrane (ERM), and retinal vascular disorders An occurrence of CME in the fellow eye following previous cataract surgery Recent history of NSAID therapy (topical or oral) Any abnormality in fundus examination except for glaucomatous changes Any abnormality in pre-operative macular OCT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central Macular Thickness. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Using OCT-SD imaging. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraocular pressure. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Goldmann tonometry.;Visual acuity. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Snellen chart.;Number of medications needed to control the IOP. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Medical records.;Incidence of clinical cystoid macular edema. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Clinical Fundus examination.;Incidence of significant increase in CMT. Timepoint: Before intervention, 1 month after intervention and 3 months after intervention. Method of measurement: Defined as = 50 µm compared to the baseline in OCT imaging. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Masoud Mirghorbani
Tehran University of Medical Sciences
Outcome results
None listed