Recurrent Implantation failure. Complication associated with artificial fertilization, unspecified
Conditions
Interventions
5 days before to 14 days after the embryo transfer, patients will receive 1-3 mg of Rapamycin every day..
Treatment - Drugs
5 days before to 14 days after the embryo transfer, patients will receive 1-3 mg of Rapamycin every day.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients who experienced at least two implantation failure; patients with Azeri origin; Patients who did not have any type of immunotherapy in his medical history. Exclusion criteria: Patients below 18 years and above 41 years; Patients with abnormal karyotype or chromosomal disorders; patients who have bleeding problems; Patients who have chronic disorders such as diabetes; Patients who have HIV, HCV or HBV positive tests; Patients who have a history of asthma and allergies to certain drugs; patients who have uterus anomalies.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Embryo Implantation. Timepoint: 2 month after intervention. Method of measurement: Laboratory tests and ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cellular and molecular changes in the immune system. Timepoint: 2 month after intervention. Method of measurement: Flow cytometry, ELISA, RT-PCR. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehdi Yousefi
Tabriz University of Medical Sciences
Outcome results
None listed