Hemodynamic changes during tracheal intubation

Comparison of intubating conditions and hemodynamic changes using propofol-succinyl choline with remifentanil-propofol for tracheal intubation in patients under General Anesthesia for upper Extremity surgeries

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016081310765N10

Enrollment

Registered

2016-12-21

Start date

2016-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Failed or difficult intubation. Failed or difficult intubation

Interventions

Intervention 1: Remifentanil will be IV injected through 5-10 seconds, then propofol 2.5 mg/kg administered through 30 seconds. After 60 seconds mask ventilation with oxygen 100% they will be intub

Treatment - Drugs

Remifentanil will be IV injected through 5-10 seconds, then propofol 2.5 mg/kg administered through 30 seconds. After 60 seconds mask ventilation with oxygen 100% they will be intubated with suitab

Fentanil 50 µg will be IV injected then propofol 2.5 mg/kg administered through 30 seconds. Then sucsynilcoline 1 mg/kg IV will be administered after 60 seconds mask ventilation with oxygen 100

Eligibility

Sex/Gender

All

Age

18 Days to 7 Days

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidates to upper limb surgeries under general anesthesia; patients with ASA class I and II; patients with Mallampaty grade 1 or 2; requested to contribute on study Exclusion criteria: patients with ASA class III or higher; cardiovascular or respiratory patients; brain vascular diseases; intramuscular diseases; patients with Mallampaty grade 3 or higher; obese patients; patients with romanticismal disease; laryngeal or vocal cords disease; preoperative horsness

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood Pressure. Timepoint: Imediatly after induction of anesthesia, 3 and 5 minute after induction. Method of measurement: Non invasive BP.;Heart rate. Timepoint: Imediatly after induction of anesthesia, 3 and 5 minute after induction. Method of measurement: With electrocardiography.	—

Secondary

Measure	Time frame
Heart rate. Timepoint: Imediatly after induction of anesthesia, 3 and 5 minute after induction. Method of measurement: With Elecrocardiogram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSousan Rasouli

Reaserch center, Tabriz University of Medical Scienses

Rasooli_s@yahoo.com+98 41 3338 9336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026