The effect of acupuncture in migraine prophylaxis

The effect of acupuncture as an adjunct to Amitriptyline and Propranolol in migraine prophylaxis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160813029327N17

Enrollment

100

Registered

2018-09-24

Start date

2017-06-22

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

migraine. Migraine, unspecified

Interventions

Intervention 1: The first group (control) received 25 mg amitriptyline at night and 20 mg propranolol twice daily for migraine prophylaxis. Intervention 2: The second group (intervention) received 25

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: People with migraine that age between 18 to 60 Number of attack more than 4 along 4 week The patient’s tendency to participate in the study

Exclusion criteria

Exclusion criteria: Other kinds of headache like tension headache and ... . Taking another drugs for migraine prophylaxis Pregnancy and Lactation Depression or Parkinsonism Tendency to quit of study Hypersensitivity to medication treatment

Design outcomes

Primary

Measure	Time frame
The average number of migraine attacks. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.;Intensity. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Pain intensity questionnaire based on Pain Intensity Numerical Rate Scale.;Duration of attacks. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.;Nausea and Vomiting frequency. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.	—

Measure

Time frame

The average number of migraine attacks. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.;Intensity. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Pain intensity questionnaire based on Pain Intensity Numerical Rate Scale.;Duration of attacks. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.;Nausea and Vomiting frequency. Timepoint: 4 weeks before the start of the study, after 4 weeks, at the end of the study and 4 weeks after completion of the study. Method of measurement: Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Abrishami

Islamic Azad Univercity of Pharmaceutical Sciences

r_abrishami@iaups.ac.ir+98 21 6393 5258

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026