Effect of naproxen on the post-operative pain of thoracotomy

Effect of naproxen on post-operative pain of thoracotomy, a randomized, blinded diclofenac control study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160813029327N16

Enrollment

Registered

2018-07-28

Start date

2017-02-18

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing thoracotomy due to various conditions, eg. hydatic cyst, metastasis, mediastinal mass..

Interventions

Intervention 1: The intervention group 1 receives 500 mg naproxen suppository 30-60 minutes before surgery. Intervention 2: The intervention group 2 receives diclofenac suppository 100 mg at the time

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients who are between 18 and 65 years of and in proper physical condition for thoracotomy surgery. Tendency to participate in the study and having consent form

Exclusion criteria

Exclusion criteria: Patients with a history of gastric ulcer disease Serious complications from non-steroidal anti-inflammatory agents Bleeding disorders Kidney failure Patients that used non-steroidal anti-inflammatory drugs.

Design outcomes

Primary

Measure	Time frame
Pain evaluation. Timepoint: 0, 30, 60, 90 minutes, 2, 4, 6, 10, 24 hours after surgery. Method of measurement: VAS (Visual Analogue Scale) technique.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Abrishami

Islamic Azad University

r_abrishami@iaups.ac.ir+98 21226400515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026