The effect of silybum marianum in the treatment of tinnitus

Clinical trial of silybum marianum in the treatment of tinnitus, a double blind randomized study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160813029327N13

Enrollment

Registered

2018-07-10

Start date

2018-05-22

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus. Tinnitus

Interventions

Intervention 1: Intervention group: in people with inclusion criteria to be given 140mg oral silymarin tablet (Livergol (R), Gol Daru), 3 times daily, for three months. Intervention 2: Control group:

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with idiopathic tinnitus aged 18-65 years old

Exclusion criteria

Exclusion criteria: Pregnant and lacatating women History of allergy to silymarin Unwilling to complete the study

Design outcomes

Primary

Measure	Time frame
Tinnitus status. Timepoint: Before the intervention, 6 and 12 weeks after the beginning of the intervention. Method of measurement: Iowa Tinnitus Primary Function Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Abrishami

Islamic Azad University

r_abrishami@iaups.ac.ir+98 21226400515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026