Evaluation the effect of pomegranate seed oil in the treatment of gum disease

Comparison of the effect of subgingival irrigation with pomegranate seed extract & chlorohexidine after scaling on chronic periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016081229308N1

Enrollment

Registered

2016-10-03

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: intervention group 5 milliliter chlorhexidine 0.2 % solution as subgingival irrigation with insulin syringe gauge 23 after final scalin and root planing. Intervention 2: intervention

Treatment - Drugs

Placebo

intervention group 5 milliliter chlorhexidine 0.2 % solution as subgingival irrigation with insulin syringe gauge 23 after final scalin and root planing

intervention group 5 milliliter pomegranate seed extract as subgingival irrigation with insulin syringe gauge 23 after final scaling and root planing

control group 5 milliliter distilled water used as subgingival irrigation with insulin syringe gauge 23 after final scaling and root planing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with moderate to severe chronic periodontitis; participants have at least one posterior tooth with a pocket depth of 5 mm or more in three different quadrants of the dentition. Exclusion criteria : allergy to pomegranate; smoking habit; overhang restorations; requiring antibiotic prophylaxis prior to dental treatment; doing scaling and root planing or getting antibiotics within the preceding three months; pregnant women; medical condition that may comprise periodontal tissue.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Periodontal pocket. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: mili meter with Williams probe.;Gingival index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: Loe and sillnes score system.;Bleeding index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: lenod score system.;Plaque index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: in term of percentage by oleary method.	—

Measure

Time frame

Periodontal pocket. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: mili meter with Williams probe.;Gingival index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: Loe and sillnes score system.;Bleeding index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: lenod score system.;Plaque index. Timepoint: at baseline - 6 weeks after the final scaling session. Method of measurement: in term of percentage by oleary method.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zahra Emami

Shiraz University of Medical Sciences

Emamiz@sums.ac.ir+98 71 3626 4271

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026