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Effect of Ketofol and Fenofol on sedation and analgesia

Comparison of Propofol and Ketamine Combination (Ketofol) and Propofol and Fentanyl combination (Fenofol) on sedation and analgesia in patients undergoing lumpectomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160812029310N4
Enrollment
64
Registered
2018-07-01
Start date
2017-02-28
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: sedation. Condition 2: analgesia.

Interventions

Intervention 1: Intervention group 1: Initially, personal consent is obtained from the patients. Then the patient is placed on the operating bed and attached standard monitoring devices including puls

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: The patients at the age of 15-70 years old ASAIII With breast cancer ASA I,II candidates for lumpectomy

Exclusion criteria

Exclusion criteria: Difficult airway management mental disorder allergy to drugs head Injury Severe cardiovascular disease Severe pulmonary disease history of Epilepsy or Seizure

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure. Timepoint: Before and after the intervention, one, three, five, ten minutes after induction of anesthesia and then at 60 and 120 minutes. Method of measurement: Non invasive blood pressure Automated.;Heart rate. Timepoint: Before and after the intervention, 1, 3, 5, 10 minutes after induction of anesthesia and then at 60 and 120 minutes. Method of measurement: Pulse oximetry device.;Arterial oxygen saturation. Timepoint: Before and after the intervention, 1, 3, 5, 10 minutes after induction of anesthesia and then at 60 and 120 minutes. Method of measurement: Pulse oximetry device.

Secondary

MeasureTime frame
Intensity of pain. Timepoint: At times 1, 3, 5, 10 minutes after induction of anesthesia and then at 60 and 120 minutes after induction of anesthesia. Method of measurement: Using criterion VAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Nazemroaya

Esfahan University of Medical Sciences

behzad_nazem@med.mui.ac.ir+98 31 3224 7233

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026