Compare the efficacy of Metoclopramide and Dexamethasone with Metoclopramide itself in the control of vomiting due to mild head trauma in children between the ages of 8-2 years

Comparison of Metoclopramide and Dexamethasone versus Metoclopramide itself in the control of vomiting due to minor head trauma in the age range of 2-8 years old

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016081128944N1

Enrollment

Registered

2016-08-11

Start date

2016-07-26

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vomiting caused by minor head trauma. Vomiting associated with other psychological disturbances

Interventions

Intervention 1: The intervention group In this study, one group of patients will receive 0.15mg/kg Metoclopramide and also 0.15 mg/kg Dexamethazone intramuscularly. Then, after 20,40 and 60 minutes

Treatment - Drugs

The intervention group In this study, one group of patients will receive 0.15mg/kg Metoclopramide and also 0.15 mg/kg Dexamethazone intramuscularly. Then, after 20,40 and 60 minutes, and also each

Control group: In this study, this group will receive 0.15mg/kg Metoclopramide and also, 0.15mg/kg distilled water (Placebo) intramuscular. Then, after 20, 40 and 60 minutes, and also each hour (until

Eligibility

Sex/Gender

All

Age

2 Years to 6 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with GCS 14-15; aged between 2-8 years; minor trauma associated with vomiting and normal CT. Exclusion criteria: unstable hemodynamics; neurological disorders; restless leg syndrome; the use of antiemetic medications during past 8 hours; recent receipt of injectable drugs; Nausea and vomiting caused by motion sickness; chemotherapy and radiotherapy; allergy to metoclopramide or dexamethasone; having contraindications for dexamethasone; simultaneous treatment with corticosteroids; diarrhea and a child who is under treatment with sedative drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vomiting caused by minor head trauma. Timepoint: 20 minutes before the Intervention. Method of measurement: VAS test.	—

Secondary

Measure	Time frame
Vital signs (respiratory rate, heart rate) and their alertness. Timepoint: after 20,40 and 60 minutes, and also hourly (until 4 hours after the intervention of patients' vital signs). Method of measurement: Pulse Oximeter, manometer, counting the respiratory rate.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdis vakili

Ahvaz Jundishapur University Of Medical Sciences, Ahvaz, Iran

mahdisvakili@yahoo.com+98 61 3336 7543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026