The impact of aggressive hydration therapy with lactated Ringer’s solution before procedure on outcomes after Endoscopic Retrograde CholangioPancreatography

Comparing Short-term effects of aggressive hydration therapy with lactated Ringer’s solution before cholangiopancreatography for prevention of complications compared with not using of serum before the Endoscopic retrograde cholangiopancreatography

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201608101213N4

Enrollment

240

Registered

2016-09-18

Start date

2016-07-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatitis. Acute pancreatitis

Interventions

Intervention 1: For the intervention group, aggressive fluid therapy, a dose of 20 ml / kgof Ringer lactate within 90 minutes before endoscopy And 3 mL / kg /h is given during ERCP with 3 to 8 mL / k

Treatment - Drugs

For the intervention group, aggressive fluid therapy, a dose of 20 ml / kgof Ringer lactate within 90 minutes before endoscopy And 3 mL / kg /h is given during ERCP with 3 to 8 mL / kg /h will contin

For the control group, 1.5 mL / kg /h during ERCP is Ringer lactate which will continue up to 8 hours after ERCP.

Eligibility

Sex/Gender

All

Age

No minimum to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Indication of endoscopic retrograde cholangiopancreatography; Consent of enrollment in study and Exclusion criteria:Acute cholangitis; Sepsis; Pregnancy; Age above 70 years; Chronic pancreatitis; Acute pancreatitis due to biliary stone; Risk of fluid overload; Peripheral edema; Pulmonary edema; Electrolyte disturbance for example Na over 150 or below 130; History of endoscopic retrograde cholangiopancreatography per formation with sphincterotomy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post endoscopicretrograde cholangiopancreatography pancreatitis. Timepoint: 2,8 and 24 hours after intervention. Method of measurement: Questionnaire.	—

Secondary

Measure	Time frame
Hyper amylasemia. Timepoint: 2,8 and 24 hours after intervention. Method of measurement: U/L.;Pain. Timepoint: 2,8 and 24 hours after intervention. Method of measurement: Visual analouge pain scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Manouchehr Khoshbaten

Tabriz University of Medical Sciences

Khoshbatenm@tbmed.ac.ir+98 41 3334 7554

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026