Effect of Silimarina (Livergo) on liver enzymes in patients taking Isotretinoin

Comparative effect of Silimarina (Livergo) with placebo on liver enzymes in patients taking Isotretinoin

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016080814229N5

Enrollment

Registered

2016-09-02

Start date

2016-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

????. Acne vulgaris

Interventions

Intervention 1: Group 1 (intervention): 140 mg Livergol capsules daily for 30 days. Intervention 2: Group 2 (control):Starch capsules daily for 30 days.

Treatment - Drugs

Group 1 (intervention): 140 mg Livergol capsules daily for 30 days

Group 2 (control):Starch capsules daily for 30 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria included: Acne; treatment with isotretinoin; aged between 15 -50 and Consent to participate in research. Exclusion criteria included: Liver disease; history of alcohol use; pregnancy and sensitivity to Livergo.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Alanine Transaminase. Timepoint: Before and after 30 days. Method of measurement: U/L - Laboratory kit.;Aspartate transaminase. Timepoint: Before and after 30 days. Method of measurement: U/L - Laboratory kit.;Alkaline Phosphatase. Timepoint: Before and after 30 days. Method of measurement: U/L - Laboratory kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadi Jafari Manesh

Arak University of Medical Sciences

nurse_science@yahoo.com+98 86 3417 3503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026