Head trauma. Other intracranial injuries, Intracranial injury with prolonged coma,Traumatic subarachnoid haemorrhage,Traumatic subdural haemorrhage,Diffuse brain injury,Focal brain injury,Epidural haemorrhage,
Conditions
Interventions
Intervention 1: Intervention of this research is a ventilation mode is called Airway Pressure Release Ventilation that will be applied through ventilator and tracheal tube for half an hour. This mode
Intervention of this research is a ventilation mode is called Airway Pressure Release Ventilation that will be applied through ventilator and tracheal tube for half an hour. This mode is an inverse ra
The patients in group 2 will receive APRV for two hours and after that ABG will be taken half an hour and two hours after changes. Then ventilator mode will be switched to SIMV for two hours and ABG w
Sponsors
Vice Chancellor for research of Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 15 and 60 years; patients suffering from traumatic brain injuries who are intubated and are under mechanical ventilation with SIMV mode; stable hemodynamic (MAP more than 70 mm Hg for at least 30 minutes before the start of the study); Glasgow Coma Scale <9 ; no history of chronic obstructive pulmonary disease (COPD); Exclusion criteria: unstable hemodynamic (MAP <70); need to CPR.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pressure of arterial oxygen. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Atrial blood gas (ABG).;Pressure of arterial CO2. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Atrial blood gas (ABG).;Aterial oxygen saturation. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Monitore. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean artery pressure. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Sphygmomanometer.;Heart rate. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Number in minute.;Systolic pressure. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHassan Khalili
Sabzevar University of Medical Sciences
Outcome results
None listed