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Assessment of serum level of insulin-like growth factor 1 in the Blood of gastric cancer patients

Assessment of insulin-like growth factor I and its signaling pathways in the serum and the tissue of gastric cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016080318745N10
Enrollment
75
Registered
2016-08-30
Start date
2016-08-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer. Stomach, unspecified

Interventions

The patients with dyspepsia will be divided into two groups: non-gastric and gastric cancer. After inclusion, 10 cc of whole blood and the tumor tissue sample of all the patients under endoscopy will
Diagnosis

Sponsors

Tehran University of Medical Sciences
Lead Sponsor
Iran University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria include: 40-70 years old patients with dyspepsia; the patients with written consent; the patients with no history of cancer or special disease. Exclusion criteria include: the patients with diabetes type 1 or 2; the patients with obesity; the patients with smoking.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum level assessment of insulin-like growth factor I. Timepoint: after endoscopy procedure. Method of measurement: Elizza.

Secondary

MeasureTime frame
The expression of the genes involved in insulin-like growth factor 1 signaling pathway. Timepoint: One time after sampling. Method of measurement: Real-time PCR.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Mohammad Alizadeh

Cancer Research Center, Cancer Institute of Iran

aalizadeh@sina.tums.ac.ir+98 21 6119 2501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026